Updated Analysis of Phase III ALSYMPCA Study for Bayer’s Investigational Compound Radium-223 Dichloride to be Presented at the 48th Annual ASCO Meeting

Click to view news release full screen

LBA #4512

WAYNE, N.J., June 4, 2012 /PRNewswire/ — Bayer HealthCare today announced updated data from the pivotal Phase III ALSYMPCA (ALpharadin in SYMptomatic Prostate CAncer) trial for its investigational drug radium-223 dichloride[*] in men with castration-resistant prostate cancer (CRPC) and symptomatic bone metastases.[1] Radium-223 dichloride significantly increased overall survival (HR=0.695, p=0.00007).(1) The median overall survival (OS) benefit in patients given radium-223 dichloride increased from 2.8 months at the time of the pre-planned interim analysis in June 2011 to 3.6 months in this updated analysis [14.9 months in the radium-223 dichloride group plus best standard of care (BSC) vs. 11.3 months with placebo plus BSC].(1) These and additional data will be presented as a late-breaking abstract in an oral abstract session on June 5th at the 48th Annual Meeting of the American Society of Clinical Oncology (ASCO) in Chicago (LBA No. 4512).

“Bone metastases are one of the main causes of morbidity and death in patients with castration-resistant prostate cancer, yet until now there has been little progress made towards developing therapies that treat the cancer when it has spread to the bone,” said Dr. Chris Parker of The Royal Marsden NHS Foundation Trust, London, and The Institute of Cancer Research, London, and principal investigator of ALSYMPCA.

In addition to improving OS, radium-223 dichloride led to a statistically significant delay in the time to first skeletal-related event (SRE) in men with CRPC with bone metastases.(1)

The overall safety and tolerability profile for radium-223 dichloride was consistent with previous study results. The most common hematologic adverse events included anemia (31% vs. 31%), neutropenia (5% vs. 1%) and thrombocytopenia (12% vs. 6%) for patients receiving radium-223 dichloride compared to placebo. With respect to Grade 3 and 4 adverse events, the most common events included anemia (13% vs. 13%), neutropenia (2% vs. 1%) and thrombocytopenia (6% vs. 2%). The most common non-hematologic adverse events included bone pain (50% vs. 62%), nausea (36% vs. 35%), diarrhea (25% vs. 15%) and vomiting (19% vs. 14%) for patients receiving radium-223 dichloride as compared to placebo. With respect to Grade 3 to 4 adverse events, the most common events included bone pain (21% vs. 26%).

“These updated survival data with radium-223 dichloride are encouraging and may provide a new treatment option for men who are fighting prostate cancer at its most aggressive stage,” said Pamela A. Cyrus, M.D., Vice President and Head of U.S. Medical Affairs, Bayer HealthCare Pharmaceuticals. “Radium-223 dichloride is a chief example of Bayer’s commitment to researching innovative therapies for diseases where few options currently exist for patients.”

ALSYMPCA Trial Design 

The ALSYMPCA trial was a Phase III, randomized, double-blind, placebo-controlled international study of radium-223 dichloride plus BSC compared with placebo plus BSC in patients with symptomatic CRPC that has spread to the bone. The trial enrolled 921 patients in more than 100 centers in 19 countries who were docetaxel ineligible or intolerable or had failed prior docetaxel therapy. The study treatment consisted of up to six intravenous administrations of radium-223 dichloride or placebo each separated by an interval of four weeks.

The primary endpoint of the study was OS. Secondary endpoints included time to occurrence of SRE, changes and time to progression in PSA and ALP, safety, and impact on quality of life measures.

ALSYMPCA was initiated by Algeta ASA (Oslo, Norway) in June 2008.

About Radium-223 Dichloride

Radium-223 dichloride, formerly referred to as radium-223 chloride, is an investigational alpha-particle emitting pharmaceutical (a pharmaceutical containing an alpha-particle emitting nuclide) in development for CRPC patients with bone metastases.

In September 2009, Bayer signed an agreement with Algeta for the development and commercialization of radium-223 dichloride. Under the terms of the agreement, Bayer will develop, apply for global health authority approvals, and commercialize radium-223 dichloride globally. In April 2012, Algeta announced that it has exercised its option to co-promote radium-223 dichloride for the treatment of CRPC patients with bone metastases in the United States in accordance to their agreement with Bayer.

Radium-223 dichloride is an investigational agent and is not approved by the U.S. Food and Drug Administration (FDA), the European Medicines Agency (EMA), or other health authorities. Bayer plans to file radium-223 dichloride with regulatory authorities based on the ALSYMPCA data in the second half of 2012.

About CRPC and Bone Metastases

Prostate cancer is the most common cancer among men in the United States and other developed countries (other than skin cancer).[2] Approximately 15% of prostate cancer cases are considered regional or distant, which means that the cancer has spread beyond the prostate to nearby or distant areas of the body (metastasis).[3] 

A majority of men with CRPC have radiological evidence of bone metastases.[4] Once the cancer cells settle in the bone, they interfere with bone strength, often leading to pain, fracture and other complications that can significantly impair a man’s health.[5] Bone metastases secondary to prostate cancer typically target the lumbar spine, vertebrae and pelvis.[6] In fact, bone metastases are the main cause of morbidity and death in patients with CRPC.[7]

About Bayer HealthCare Pharmaceuticals Inc.

Bayer HealthCare Pharmaceuticals Inc. is the U.S.-based pharmaceuticals business of Bayer HealthCare LLC, a subsidiary of Bayer AG. Bayer HealthCare is one of the world’s leading, innovative companies in the healthcare and medical products industry, and combines the activities of the Animal Health, Consumer Care, Medical Care, and Pharmaceuticals divisions.  As a specialty pharmaceutical company, Bayer HealthCare provides products for General Medicine, Hematology, Neurology, Oncology and Women’s Healthcare.  The company’s aim is to discover and manufacture products that will improve human health worldwide by diagnosing, preventing and treating diseases.

Bayer® and the Bayer Cross® are registered trademarks of Bayer. 

Forward-Looking Statement
This news release may contain forward-looking statements based on current assumptions and forecasts made by Bayer Group or subgroup management. Various known and unknown risks, uncertainties and other factors could lead to material differences between the actual future results, financial situation, development or performance of the company and the estimates given here. These factors include those discussed in Bayer’s public reports which are available on the Bayer website at www.bayer.com. The company assumes no liability whatsoever to update these forward-looking statements or to conform them to future events or developments. 

[*] Previously referred to as radium-223 chloride.

[1] Parker C et al. Updated analysis of the phase III, double-blind, randomized, multinational study of radium-223 chloride in castration-resistant prostate cancer (CRPC) patients with bone metastases (ALSYMPCA) [abstract]. ASCO 2012.

[2] American Cancer Society. Prostate Cancer: Detailed Guide. February 27, 2012. Available at: http://www.cancer.org/acs/groups/cid/documents/webcontent/003134-pdf.pdf. Accessed May 17, 2012.

[3] National Cancer Institute, Surveillance Epidemiology and End Results (SEER). Stage Distribution (SEER Summary Stage 2000); Prostate, All Ages, Male 2000-2008.

[4] Sartor, O. “Radiopharmaceutical and chemotherapy combinations in metastatic castrate-resistant prostate cancer: a new beginning.” JCO. 2009;15:2417-2418.

[5] American Cancer Society. Bone Metastases: Detailed Guide. May 3, 2012. Available at: http://www.cancer.org/acs/groups/cid/documents/webcontent/003087-pdf.pdf. Accessed May 17, 2012.

[6] Bone and Cancer Foundation. Questions & Answers about Prostate Cancer Bone Metastases and Treatment-Related Osteoporosis. Available at: http://www.boneandcancerfoundation.org/pdfs/prostate-cancer-qa.pdf. Accessed May 17, 2012.

[7] Lange PH, Vasella RL. “Mechanisms, hypotheses and questions regarding prostate cancer metastatic to bone.” Cancer & Metastasis Reviews.1999;17:331-336.

SOURCE Bayer HealthCare

Back to top


PR Newswire: General Business

Working Toward Your Success In Article Promotion

After you write the article, your immediate goal is to promote it and put it in the hands of those who are most likely to be interested. This is easier said than done sometimes. You have many choices when it comes to gaining a customer base. The tips presented below should help you launch a successful article advertising campaign.

Do not use too many keywords in your headlines. Two major components of article syndication are headline content and proper keywords. Headlines should grab your readers’ attention. Determine if a person will want to read the headline and make sure it is captivating to your audience.

The quality of your articles matters, even if article advertising is only a way to get more back-links. Having top-notch content will help you get backlinks and traffic. It really is a win-win situation.

If the content of your article will allow it, add numbers into your title. Numbers in titles can help increase viewers. Monitor your readership and take note of which titles generate the most interest.

TIP! Try to expand the amount of article directories that you focus on. There are hundreds of sites you could use for article submission.

Link to other articles within your own site. This can be helpful if people are copying your articles. You may not know that someone copies it illegally, but you will still be able to show your article.

Make your own original logo! It is a common misconception that easily recognized logos are the exclusive domain of large companies. Readers who visit your site often will come to recognize and trust your logo, and seeing it on another blog or forum may remind them to visit. Give you audience something to remember your site by. Develop a simple logo that will stick in people’s minds.

Longtail Keywords

After you’ve been creating articles for quite some time, you’ll have quite a bit of work that goes all over the Internet. Create an eBook that contains your best articles and sell it or use it as a free promotion to your customers. People will then share your high-quality ebook with each other, which will help advertise your business.

TIP! The more people that see your content, the more successful you can become. This does not mean that your content should only have a general focus.

When you first begin article marketing, target longtail keywords. By utilizing this method, you will find your articles heading the top search engine results. Additionally, most longtail keywords get searched for about fifty to sixty times each month, so if you are trying to market a specific product or service and the keywords are highly targeted, you could get a few orders.

Do not make your articles sound like an advertisement. If your articles aren’t interesting, you readers will leave. If your writing is interesting and informative, readers will return to read more of your articles.

Research the types of ads your customers would be interested in viewing. Also, you don’t need to be scared of changing your ads up every once in a while by using various graphics or text. Trial and error will help you find the best content for your client base.

Remember to keep track of everything you submit to article directories. Review the stats of each article, including the average amount of time your visitors view each article and how many visitors there are, and you can discover the topics that are the most attractive for your visitors. You can then cater your articles more towards your audience.

TIP! Make sure to create a creative, interesting short description. This should be found beneath the title in a search engine result page.

A key point in article advertising is to always have original content. When indexing articles, Google ranks fresh content more favorably than it does duplicates. Writing services are available that provide cheap content creation. Compare each of their rates to find a company that is affordable.

Don’t underestimate the importance of good title tags. It’s important that keywords are included in this that have something to do with your site’s content. Try to expose in your webpage that this tag is unique from all other sites.

Always write about subjects that would be entertaining to the readers of your website. Always write informally and in a friendly way. Even when you are writing about something technical, make it an easy read by using layman’s terms. Do not write boring content that will alienate your readers.

You need to be aware of SEO and general marketing techniques if you want to be a successful article marketer. SEO will help to increase the position of your articles in the SERPs. Simply distributing articles is insufficient. You need to have a strategic approach to your article marketing venture and you must keep an ultimate goal at the forefront of your mind.

TIP! Regardless of the topic, you should always try to include only what is needed and as briefly as possible. While you must show ideas that need more of an explanation, you have to get rid of excess content when you are able to.

Put well-written and informative articles on your site. There is no better way to build a loyal following than showing a concerted effort to provide valuable content for free. Yes, making a sale is important, but when you give quality info, you first build that trust, making them more likely to buy.

If you’ve seen celebs using your products, ask their permission to promote this great news. Such free publicity can generate lots of demand. You should never engage in making erroneous claims regarding celebrity use of your product because that can expose you to legal issues.

Your article advertising campaign should be an ongoing project. Look for problems, and locate products that address them. Garner demand with good articles that offer good products, and call readers to action at the end of your articles. Do that every time, and you will get the results you want to see.

Articles should not ramble on and on. You don’t want to have an article that contains too much fluff that isn’t interesting. 250 to about 500 words should be your limit. Maintain it intersting for readers, so they read it completely and do not move along to another site out of boredom.

TIP! No matter how tempting it is, never take on a project that fails to interest you. While you may think you have your writing voice trained, it’s hard to hide what you’re really thinking completely.

As you’ve seen, writing is only part of the process; finding readers is another big part. Finding this readership may feel difficult at first, but with time and practice, it becomes much easier. Utilize the excellent ideas presented here, and your readership will expand significantly

Varied Article Marketing Techniques To Try With Your Business

One of the most useful tools for businesses that wish to promote their products is article syndication. It is simple and fairly cheap to do. Keep reading if you would like to develop your own article syndication campaign.

Write material that will stand the test of time. Avoid topics that are only true the moment or day you write about them. An article which is useful in a year won’t be wasting bandwidth. Writing timeless pieces will help increase your readership.

Try to reduce the uninteresting articles that you write as the year goes on. Even the best writers often have problems concealing boredom or apathy while writing about certain topics. Boredom will turn readers off, and make them look elsewhere for content that is tuned in. Write about things you’re passionate about, and that passion will be obvious in your writing.

Your articles must not be time-sensitive. Find topics that generate interest now and will in the future. You want readers to be able to be engaged even if they look at material that you have written over a year ago. New material keeps things fresh, which is a great way to hold readers.

TIP! In any ambitious article marketing strategy, the marketer’s articles will wind up posted far and wide across the Internet. The article must always include working links that lead to the site being promoted.

When you’re creating your articles, make sure that they are relevant to items like your keywords and your links. It is important that everything, including the content, keywords and links, are related. If the connections don’t make sense, the search engine does not know what is searching for.

Your articles should be relatively short, 500 words should do it, and should include an introduction that grabs the reader. People have limited focus, so reel them in at the very beginning. You can always add more explanatory information later in your article, but make sure the first line or two will keep them reading.

You should always place bullet points or numbers in your articles. If you implement this strategy it will make the content you provide easier for the reader to understand and unforgettable. To deliver content with more emphasis, you can try presenting your information to your audience through bullets or numbers.

Make sure that the first paragraph in your article is very well-written. Search engines and readers think that the beginning paragraph is the critical part of your article. Including the best information in this section is a good way to grab their attention. Be sure it is engaging, and do not include everything that is relevant. Instead, pique your visitor’s interest so that they will continue reading your article.

TIP! Be skeptical of the claims some writers make. If they claim to have an exclusive method for success in article marketing, they need to prove it.

Each paragraph should include only three to five sentences; each article should use between 500 and 700 words. Since that is the criteria established by most directories, following those guidelines will make it simpler to distribute your articles. Blog entries can be shorter than articles; reach for the goal of no more than four hundred words per post.

Marketing through articles is a great way for a business to promote what they offer to the public. It is quite simple and affordable. The tips you just read should help you create quality articles and share them with your audience.

How You Can Go From Amateur To Pro In Article Submission

Although the power of article promotion is clear, you may be hesitant to jump into the field if writing is not your cup of tea. Seeing good results from your articles is a matter of self-education and a lot of dedicated effort. This article can help you remain optimistic about your success.

Give valuable information to your readers. Prospective customers are interested in finding something valuable in your articles. If they do, they are more likely to come back to you for more.

Add new articles as often as possible. Search engine crawlers scour your site and make a note of how often you make changes to the index with new content. The more content you post, the higher the search engines rate your site and the more visitors you have.

If users are allowed to post their comments on your site, make sure to utilize the link attribute “no follow”. When the user leaves spam or unwanted site links, the web crawlers will then be notified of that “no follow” attribute. They will not follow that site’s link. That stops you from getting negative attention from those crawlers, and helps you avoid linking to sites that are just spam.

TIP! Give some thought to outsourcing. If you don’t have time for article writing, you can hire a freelance writer.

In the most successful article marketing campaigns, the articles will be shared all over the Internet. This is good news, but you must have links included that take readers back to your website. This will help increase your audience and make search engine indexing go much smoother. Broken or missing links negatively affect the benefits of posting articles.

Familiarize yourself with any rules your article directory might have. Submission guidelines differ from directory to directory.

Be original and let your own style shine though when writing your articles. By revealing your true personality, you can gain authenticity and draw readers. Be honest and original in your writing and see how fast your audience grows.

In order to get more of a presence on the web, utilize tools. There are many tools available that will submit your article to article directories for you, hundreds at a time. While some do have a small cost, others are free. Find these tools so that you can get more readers without spending a fortune.

TIP! Do not overload your article with keywords. Overusing a keyword results in poor responses from both readers and trackers.

Don’t use automatic writing services for article marketing purposes. Although such a service will be able to supply you with huge quantities of articles very quickly, the quality of said articles will not be guaranteed. Many of them probably won’t even use standard English. Do yourself a favor and stick to writing your own content; once you get the hang of it, you can write more articles in a shorter period of time.

There are a lot of things you need to consider when you are researching a niche. Hopefully, this article provides you with the intricate knowledge and inspiration you need to get started on your own. It will require a good sense of business and direction on your end, but with the added help of this article, you can achieve greatness with a slighter ease.

Business Q&A: What brand of jeans are good for my body type?


brand question by : What brand of jeans are good for my body type?
I am 5′ 8″ and I am a size 10/11. (It varies from brand to brand.) I have No hips and a flat butt. All the jeans I have tried on end up giving me a lot of extra fabric in the front because I have no hips or butt. Basically I need a good pair of jeans for someone without a butt.
All suggestions are appreciated.

brand best answer:

Answer by Ren
I just went to Levi’s yesterday and saw they had a new line of jeans that not only goes by size, but also curve. They have jeans for girls with a lot of curve, and for girls with no curve. I bought a pair and I love them (we have a similar body type/size)

Continue reading Business Q&A: What brand of jeans are good for my body type?

Want To Get Better At Article Promotion? Try These Ideas!

You are interested in gaining information regarding article syndication, and it is important to do so in a simple way. Keep reading this article if this sounds like you. This article explains several good article syndication strategies.

For your emails, make sure you include great content. Sending out junk emails will only give you a bad name and these days they are actually unlawful. Include information that your customers actually need so that they are pleased to get your emails. If you spam people, you will lose customers.

Use controversy to write intriguing articles. Create arguments for or against a celebrity’s actions or a particular company’s products. This helps you get more publicity since others will then link your personal blog. If your content is high quality, which it should be if you edit it properly, injecting controversy will revive your blog and boost your reputation as an authority in your field.

Even if you are pushing a product, your articles should be fun to read. Write your articles in a friendly and informal style. Even technical or difficult subjects can be addressed in an easier-to-read style. Dull content will bore your readers quickly.

TIP! Provide your article’s audience with relevant and useful content. The more your reader gets from reading your article, the more likely he or she will read your next article.

After you have created content for a while, your articles will be throughout the internet. Compile your best work to create an eBook. You can then sell the eBook (or even give it away) to promote your business. If you have a quality eBook, it will be shared by many of your readers and bring more business and traffic to your website.

Take the time to consider outsourcing your articles. Hire a writer if you lack the time or skills to do the articles yourself. It isn’t free, but it is effective and will build site traffic.

When using a article directory, know what they require. You should understand that there are different guidelines for submission for each directory.

If you do it right, your articles may be spread all over the Internet. This is entirely positive – as long as the articles retain working links back to the author’s website. These links will boost a websites SEO and bring in new readers and potential customers. Broken or missing links will adversely affect your article marketing, so ensure you include working links in each article.

TIP! Don’t stuff your article with keywords. Overusing a keyword results in poor responses from both readers and trackers.

Article Syndication

Don’t put too much faith into advice you receive from “experts” of article syndication. You have to remember that people like this make their money off of teaching article syndication, not from being successful at article submission by themselves. However, we are not saying that everything they say will be irrelevant or incorrect. Just be sure you take their intel in due course with your own experiences.

In conclusion, you should now know what article advertising consists of. Hopefully, you learned a thing or two and will use it effectively. This advice will help you throughout your article advertising career.

You really only need one keyword for every article to help boost sales. Make sure to place your keyword throughout the webpage, including the URL, title, and heading, and sub-heading. Use this word throughout the entire article. That way, your article will be easy to find in a search, which should generate increased traffic and sales.

TIP! Developing an effective attention-grabber is essential to good article marketing. A good understanding of your target audience will help you choose the most effective way to hook the attention of your readers.

Rentrak Announces Worldwide Box Office Results for Weekend of June 3, 2012

Click to view news release full screen

My news for Investors

LOS ANGELES, June 3, 2012 /PRNewswire/ — Rentrak Corporation (Nasdaq: RENT), the global leader in box office measurement, today announced the worldwide weekend box office estimates for the weekend of June 3, 2012 as compiled by the company’s Box Office Essentials™ and International Box Office Essentials theatrical measurement services.

As the trusted standard for all studio box office reporting, Rentrak provides intelligence into overnight theatre-level reporting across the global theatrical market. Coupled with the official reported data, studios are able to analyze admissions and gross results in over 50 territories using Rentrak’s suite of products.

The top-12 domestic weekend box office estimates listed in descending order, per data collected as of Sunday, June 3, 2012 are below.

  • Snow White and the Huntsman / $ 56,255,430
  • Men in Black 3 / $ 29,300,000
  • Marvel’s The Avengers / $ 20,273,000
  • Battleship / $ 4,810,320
  • Dictator, The / $ 4,725,000
  • Best Exotic Marigold Hotel, The / $ 4,600,000
  • What to Expect When You’re Expecting / $ 4,430,000
  • Dark Shadows / $ 3,860,000
  • Chernobyl Diaries / $ 3,045,000
  • For Greater Glory / $ 1,800,000
  • Hunger Games, The / $ 1,500,000
  • Bernie / $ 937,296

Full details regarding the global domestic and international box office results are listed in the table below.

Weekend BO Estimate

Weekend Release Cume










No. of Territories


Men In Black 3










Snow White And The Huntsman


















Marvel’s The Avengers










Dictator, The










Dark Shadows










What To Expect When You’re Expecting




















Best Exotic Marigold Hotel, The










All About My Wife








Chernobyl Diaries

















American Reunion









Runway Cop








Hunger Games, The










For Greater Glory








Don’t Click








Dr. Seuss’ The Lorax










Thermae Romea








Gout De Rouille Et D’os, Un
















© Rentrak    *Territory is a movie studio term for regions of the world consisting of various countries

Content in this chart is produced and/or compiled by Rentrak Corporation and its Box Office Essentials and International Box Office Essentials data collection and analytical service, and is covered by provisions of the Copyright Act.  The material presented herein is intended to be available for public use.  You may reproduce the content of the chart in any format or medium without first obtaining permission, subject to the following requirements: (1) the material must be reproduced accurately; and (2) any publication or issuance of any part of the material to others must acknowledge Rentrak as the source of the material.

About Rentrak Corporation:

Rentrak (NASDAQ: RENT) is a global digital media measurement and research company, serving the most recognizable companies in the entertainment industry. With a reach across numerous platforms including box office, multi-screen television, and home video, Rentrak has developed more efficient metrics to be used as database currencies for the evaluation and selling of media. Rentrak is headquartered in Portland, Oregon, with additional U.S. and international offices. For more information on Rentrak, please visit www.rentrak.com.



Rogers & Cowan for Rentrak Corporation

Sallie Olmsted

Amanda Bialek

(310) 854-8124 

(310) 854-8151



(Logo: http://photos.prnewswire.com/prnh/20111007/MM82941LOGO)

SOURCE Rentrak Corporation

Back to top


PR Newswire: General Business

The Best Guide On How To Succeed In Article Advertising

If you’re reading this article thinking that article marketing just can’t be as effective as people say it is, you’re wrong! You can use article syndication to connect with customers and increase your business without the need to rely on advertising gimmicks or hard-sell tactics. Like anything else, though, there are right and wrong ways to go about article submission to get the most out of your efforts. Read on to find out about the right ways to approach your article syndication campaign.

For your emails, make sure you include great content. If you don’t, the receivers may see it as spam and they’ll never enjoy the articles you want them to read. If you don’t, your subscriber list may dwindle, this, losing customers.

Post new articles to your website regularly. Your content is re-indexed on a predetermined schedule by search-engine bots. New articles continuously improve your site’s search engine rankings and also encourage return readers.

The paragraphs within your articles should remain nearly the same length as this tip. Research suggests that people may be more easily distracted while reading online than while reading a printed text. Keeping your article short and to the point will keep your readers happy.

TIP! Don’t give into the desire to bombard indexes with multiple copies of your article. There are many article indexes you should use in your article marketing efforts.

Use all the tools that are at your disposal. You can utilize all kinds of tools that can submit hundreds of articles to article directories all at once. Many cost a small fee, but many are free. Locate these for a cheap way to get more readers.

Take the advice of those experts in article submission carefully. The fact you have to take into consideration is that these people make their money by teaching people about article advertising – not by running their own article marketing programs. This doesn’t mean they have nothing useful teach you. Just remember who they are and why they’re writing as you read.

Native Language

Take the time to consider outsourcing your articles. If writing articles does not fit into your schedule, or you doubt your skills and ability, think about paying someone else to do this work. This costs money, but it can save time and help grow your business.

TIP! In all honestly, you will never find any secrets hidden in the field of article marketing and, anyone who tells you that they know something no one else does is probably lying to you. When you find stuff out about business, you also learn what you should be learning about article marketing.

Always write in your original, native language. Even if you think you can write in another language, avoid doing that and market to other groups. You might make grammar mistakes with your writing that you normally wouldn’t have in your native language. You also have an entirely different point of view, which may confuse your readers.

You need to have a large audience to find success in article syndication. This does not mean to focus your articles on the entire population on the internet. It will be more beneficial to have a small number of interested readers than a large number of uninterested readers. Always keep your target audience in mind.

Take what you’ve learned here and use it to create your own article marketing strategies, increasing your visibility and branding your content. Search engine optimization is a great way to improve visibility without spending a lot of money.

Try to create articles that help people with an issue. If you can help someone find information they were searching for, they are more likely to try to find more articles that you have written.

TIP! You should relate the information in your article in an enjoyable way and one good way to do that is to write it as if you were writing to a friend. This gives your articles a friendly tone, and it gets rid of article formality.

Be Bold When Trying Out These New Ideas For Article Advertising

A lot of enterprises follow the “If I build it, they will come” school of thought online, expecting their preferred demographic to come to them. A good online marketing strategy begins with knowing where to start. The following article will demonstrate how you can take advantage of article marketing for your business.

If your site allows for users to post comments on your webpage, you should use the “no follow” link attribute. If a user leaves spam links, search engine spiders will see the “no follow” and they won’t follow it. That stops you from getting negative attention from those crawlers, and helps you avoid linking to sites that are just spam.

An effective way in promoting your status in the industry is to enhance your online business with a blog. The articles that you post on your blog should reflect your sincerity, reliability, sense of humor, insightfulness, values and convictions. By focusing your articles on the latest trends and developments in your industry, your visitors will know that you are competent, knowledgeable and diligent.

Research can offer excellent insight into the types of ads that your target audience is most likely to enjoy. Also, don’t be afraid to change them from time to time and use different ones or different versions with various texts, colors and orientations. It takes time to learn what will work best, but it will be worth it later.

TIP! Develop a logo! Many people think logos are only used by large corporations, but smaller companies develop logos as well. A memorable logo can create trust and name recognition for visitor to your site and lead to return visits when they see your logo on another forum or blog.

Many people believe (not without cause!) that they need to produce their own content to engage in successful article promotion. You cannot write without any experience or training. Try getting proper grammar techniques down. In fact, you may have just read alliteration. Catchy articles require a certain talent. There’s more to writing than what you read in books.

Paragraphs Within

The paragraphs within your articles should remain nearly the same length as this tip. This will help to capture your audience and prevent distractions. Keep your articles and the paragraphs within them short and punchy to suit a reduced online attention span.

A blog is a great tool to promote your thought leadership in your market. The articles that you post on your site should demonstrate positive qualities like honesty, professionalism and good humor. A strong focus on current trends will show potential customers that you keep well informed and updated about your industry.

TIP! Always provide your readers with good info. People want to feel like they’re getting something from the articles they read, and if they’re happy with what they’ve read, they’re sure to come back for more.

Don’t give into the desire to bombard indexes with multiple copies of your article. There are a wide variety of article indexes for making the most of your marketing tactics. Do not submit the same article to many different index sites, though. Doing so these days is just a waste of time. The engines are all wise to that trick and no longer rank these sorts of links heavily when determining ranking.

Make the first paragraph the best one. Readers and search engines alike believe that the first paragraph of your article is the most important one. Tell them exactly what they’re going to get below. Ensure it’s interesting, but don’t spill everything right away. You want to make sure your readers read the whole article.

Take as much time as you need to learn about article advertising. It will be an eye-opener when you see how it helps your business.

Never use too many keywords in your article. Using more than five keywords throughout each of your articles will only result in your article being turned away. Your readers are happier when the article isn’t littered with the same keywords.

TIP! If you want to succeed at article marketing, you must produce high volume, high quality work. Readers appreciate having both of these provided for them.

Get Your Name Out There With These Wonderful Tips

Article syndication is a great way to get the world out about yourself or your business. When you use relevant, well-written content on your website, the traffic will come in faster. The following article will help you get started in article marketing.

Do not use your articles to sell yourself. A well-written article practically sells itself. Be sure your articles are informative so your readers will keep reading in interest.

Title Tag

Choose longtail keywords when you start out with article marketing. This ensures you get your article great page rank on Google. Also, longtail keywords tend to get searched somewhere between 50 and 60 times monthy, and therefore to market a distinct service or product with targeted keywords, it is possible to generate a decent amount of sales.

TIP! Use freebies. These freebies let customers feel like they have gotten their money’s worth so they’ll be more inclined to buy again from you.

One important tip for Internet marketing success is to fill out the title tag for your website properly. It is essential to include keywords relating to your specific site in the title tag. Also, try to describe your page in a different way.

Set aside the AP style guide for the most part and focus on crafting interesting articles that are a little less formal. Instead, create SEO friendly references in your articles and descriptions. Your writing should still be grammatically correct, but it doesn’t have to sound stringent.

If you would like to dip your toes into article promotion, look for a niche that is untouched. A market that has not yet been fully saturated offers better chances for you to gain a foothold. This will allow you to be a pioneer in a given area.

Become familiar with any site on which you submit your article marketing content. Find out about guidelines, look for tutorials, and make sure your articles meet the requirements to be published. Take some time to do any tutorial and read the guidelines for success upon submitting.

TIP! The more people that see your content, the more successful you can become. However, that doesn’t mean you need to write articles for everyone.

Avoid writing articles that come across as overt advertising. The reader does not want to be sold anything, so make sure they are informed. If your writing is interesting and informative, readers will return to read more of your articles.

Marketing articles do need to be within a certain length, but don’t worry about it while you’re writing. When writing, you should get a feeling for when your article is too wordy. Articles can be shortened later when editing. Very long pieces may be split into two articles.

A lot of effort isn’t required to be good at article syndication. It does not take a long time to begin article submission. Just remember the techniques you’ve learned here, and soon, you’ll experience success

If you want to get your business attention online, starting a blog is one of the best ways to do it. Blogging is free to use on many websites, and you can use it to engage in feedback with your visitors. Setting up a blog is simple and can help your attract new customers to your website.

TIP! Watch out for article marketing “gurus” and “experts”. Most people who write on the topic also make a living writing on the topic, meaning they possibly have never marketed an article for a business other than their own in their life.